Spinach & Artichoke Chicken Bake

Featured in: One-Pan Comforts

This comforting one-dish meal features seasoned chicken breasts topped with a creamy spinach and artichoke mixture made from Greek yogurt, mozzarella, and Parmesan cheese. Garlic and wilted spinach are combined with tender canned artichoke hearts and aromatic oregano, then spread evenly over the chicken before baking until golden and bubbly.

Ready in just 45 minutes, this high-protein, gluten-free main dish serves four and pairs beautifully with rice, quinoa, or a fresh green salad. The dish stays fresh refrigerated for up to three days, making it perfect for meal prep or family dinners.

Updated on Tue, 20 Jan 2026 15:04:00 GMT
Golden, bubbling Spinach & Artichoke Chicken Bake fresh from the oven in a ceramic dish. Save
Golden, bubbling Spinach & Artichoke Chicken Bake fresh from the oven in a ceramic dish. | hazeldish.com

The smell of garlic hitting warm olive oil still takes me back to my tiny apartment kitchen, where I first discovered that spinach and artichoke dip could somehow transform boring chicken breasts into something extraordinary. I was experimenting with lighter versions of my favorite appetizer, and honestly, the result exceeded my expectations. The chicken stayed juicy while that creamy, tangy topping developed this gorgeous golden crust that made my entire apartment smell incredible.

I made this for my sister last winter when she was recovering from surgery and needed comforting, nourishing meals. She took one bite and actually asked if I had secretly ordered it from a restaurant. Now she requests it every time she visits, and I always keep the ingredients stocked for those nights when cooking feels like too much effort but we still want something special.

Ingredients

  • Chicken breasts: Boneless and skinless work best here, but pound them to even thickness so they cook at the same rate
  • Kosher salt: Essential for seasoning the chicken properly before adding the topping
  • Freshly ground black pepper: Adds a subtle heat that complements the creamy topping
  • Olive oil: The foundation for sautéing the garlic and spinach, infusing them with rich flavor
  • Baby spinach: Fresh spinach wilts beautifully and retains more nutrients than frozen
  • Artichoke hearts: Canned artichokes are perfectly fine here, just drain them well and chop into bite sized pieces
  • Garlic: Two cloves give you that aromatic base without overpowering the other flavors
  • Greek yogurt: Whole milk Greek yogurt provides creaminess and protein while keeping things lighter
  • Mozzarella cheese: Creates that gorgeous golden, bubbly top that makes this dish so irresistible
  • Parmesan cheese: Adds a salty, nutty depth that balances the tangy yogurt
  • Dried oregano: Brings classic Italian flavor without needing fresh herbs
  • Crushed red pepper flakes: Optional, but lovely if you want a gentle background warmth

Instructions

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Preheat your oven and prep the pan:
Get your oven to 400°F and give a 9x13 baking dish a quick coating of cooking spray or olive oil.
Season the chicken:
Sprinkle both sides of each chicken breast with salt and pepper, then arrange them in a single layer in your prepared dish.
Sauté the aromatics:
Warm olive oil in a skillet over medium heat, add garlic for 30 seconds until fragrant, then toss in spinach and cook until just wilted.
Make the topping:
Combine the cooked spinach, chopped artichokes, Greek yogurt, mozzarella, Parmesan, oregano, and red pepper flakes in a mixing bowl until everything is well distributed.
Top and bake:
Spread the spinach mixture evenly over each chicken breast, then bake for 25 to 30 minutes until the chicken reaches 165°F and the topping is golden.
Rest before serving:
Let the chicken rest for 5 minutes so the juices redistribute, making each bite more tender and flavorful.
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Prepare wholesome dog meals by mixing with warm water for easy serving and homemade-style feeding.
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Tender chicken breasts topped with creamy Greek yogurt, melted mozzarella, and parmesan cheese. Save
Tender chicken breasts topped with creamy Greek yogurt, melted mozzarella, and parmesan cheese. | hazeldish.com

This recipe became my go to for new parents and anyone needing a comforting meal that does not require hours in the kitchen. Something about that combination of warm, cheesy topping and tender chicken just feels like a hug in food form.

Making It Your Own

Once you have the basic method down, this recipe adapts beautifully to whatever you have on hand. I have swapped in light cream cheese for half the Greek yogurt when I wanted extra richness, and sautéed mushrooms make a fantastic addition to the spinach mixture. Sun dried tomatoes add a lovely sweetness that balances the tangy yogurt, though I would add them sparingly since they are quite intense.

Serving Suggestions

The creamy topping pairs perfectly with something that can soak up all those delicious juices. Simple steamed rice or quinoa work wonderfully, but sometimes I just serve it alongside a crisp green salad with a bright vinaigrette to cut through the richness. Roasted vegetables would be another great option, especially something like broccoli or cauliflower that can roast on a separate sheet pan while the chicken bakes.

Storage and Reheating

This recipe actually improves overnight as the flavors meld together. Store leftovers in an airtight container in the refrigerator for up to three days, and reheat gently in the microwave or a low oven. The topping might not be quite as crispy the second day, but the flavors become even more developed and comforting.

  • Avoid freezing this dish, as the yogurt can separate and become grainy when thawed
  • If reheating in the oven, cover loosely with foil to prevent the topping from drying out
  • Let the dish come to room temperature for 15 minutes before reheating for more even warming
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Sautéed spinach and chopped artichoke hearts create a savory, tangy topping for dinner. Save
Sautéed spinach and chopped artichoke hearts create a savory, tangy topping for dinner. | hazeldish.com

There is something deeply satisfying about taking familiar flavors and turning them into something unexpected, and this chicken bake hits that perfect balance between comfort food and something just a little special.

Recipe Help & Answers

How do I know when the chicken is fully cooked?

The chicken is done when it reaches an internal temperature of 165°F (74°C) when measured with a meat thermometer at the thickest part. The topping should also be golden and bubbly.

Can I substitute Greek yogurt with another ingredient?

Yes, you can replace half the Greek yogurt with light cream cheese for extra richness, or use sour cream for a tangier flavor. Maintain the same total volume for proper consistency.

What sides pair well with this dish?

Serve alongside fluffy rice, protein-rich quinoa, roasted vegetables, or a crisp green salad to balance the creamy topping and round out your meal.

How should I store leftovers?

Store covered leftovers in the refrigerator for up to three days. Reheat gently in a 350°F (175°C) oven for about 15 minutes until warmed through, or microwave individual portions.

Can I make this ahead of time?

Yes, assemble the dish completely, cover with plastic wrap or foil, and refrigerate up to 24 hours before baking. Add 5–10 minutes to the baking time if baking from cold.

What variations can enhance the flavor?

Add chopped sun-dried tomatoes, sautéed mushrooms, caramelized onions, or crispy bacon to the topping mixture. A pinch of nutmeg or fresh basil also complements the spinach beautifully.

Spinach & Artichoke Chicken Bake

Tender chicken breasts baked under a creamy spinach and artichoke topping with Greek yogurt and melted cheese.

Prep Time
15 min
Time to Cook
30 min
Overall Time
45 min
Created by Isabel Grant

Dish Type One-Pan Comforts

Skill Level Easy

Inspired By American

Makes 4 Number of servings

Dietary Details Without Gluten

What You Need

Chicken

01 4 boneless, skinless chicken breasts (about 1.5 lbs)
02 1/2 teaspoon kosher salt
03 1/4 teaspoon freshly ground black pepper

Spinach & Artichoke Topping

01 1 tablespoon olive oil
02 2 cups fresh baby spinach, roughly chopped
03 1 (14 oz) can artichoke hearts, drained and coarsely chopped
04 2 cloves garlic, minced
05 1 cup plain Greek yogurt
06 1/2 cup shredded mozzarella cheese
07 1/4 cup grated Parmesan cheese
08 1/4 teaspoon dried oregano
09 1/4 teaspoon crushed red pepper flakes

How to Make It

Step 01

Prepare baking dish and season chicken: Preheat oven to 400°F. Lightly grease a 9x13-inch baking dish. Season chicken breasts with salt and pepper, then arrange in a single layer in the prepared dish.

Step 02

Sauté aromatics and wilt spinach: Heat olive oil in a skillet over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. Add spinach and cook until just wilted, approximately 2 minutes.

Step 03

Combine topping mixture: In a mixing bowl, combine the sautéed spinach, chopped artichoke hearts, Greek yogurt, mozzarella, Parmesan, oregano, and crushed red pepper flakes. Mix thoroughly until well combined.

Step 04

Apply topping to chicken: Spread the spinach and artichoke mixture evenly over each chicken breast.

Step 05

Bake until cooked through: Bake for 25-30 minutes, or until internal temperature reaches 165°F and the topping is golden and bubbly.

Step 06

Rest before serving: Remove from oven and let rest for 5 minutes before serving.

Tools You’ll Need

  • 9x13-inch baking dish
  • Skillet
  • Mixing bowl
  • Chef's knife and cutting board
  • Measuring cups and spoons

Allergy Details

Review each ingredient for allergens. Always reach out to a healthcare professional for help if you’re unsure.
  • Contains dairy: Greek yogurt, mozzarella, and Parmesan cheese
  • May contain eggs if using egg-enriched cheese
  • Check ingredient labels for gluten cross-contamination if sensitive

Per-Serving Nutrition

Nutritional data is for general reference only. It shouldn't replace advice from your doctor.
  • Calorie Count: 325
  • Fats: 11 g
  • Carbohydrates: 7 g
  • Proteins: 48 g