Cajun Chicken Fettuccine Velveeta

Featured in: Rustic Family Dinners

This dish combines tender chicken breasts seasoned with bold Cajun spices and seared to golden perfection. Al dente fettuccine is enveloped in a luscious sauce made from Velveeta cheese, butter, garlic, and cream, finished with Parmesan and a hint of cayenne for warmth. Fresh parsley adds a vibrant garnish, creating a rich and satisfying southern-inspired pasta experience that’s quick to prepare and perfect for any occasion.

Updated on Sun, 23 Nov 2025 08:23:00 GMT
Cajun Chicken Alfredo Fettuccine pasta: creamy, vibrant, with sliced chicken and Velveeta sauce. Save
Cajun Chicken Alfredo Fettuccine pasta: creamy, vibrant, with sliced chicken and Velveeta sauce. | hazeldish.com

A creamy, spicy pasta dish featuring tender Cajun-seasoned chicken, rich Velveeta cheese sauce, and perfectly cooked fettuccine—comfort food with a Southern twist.

This recipe quickly became a family favorite for its rich sauce and flavorful chicken. It's perfect for weeknight dinners or entertaining guests.

Ingredients

  • Chicken: 2 large boneless skinless chicken breasts 1 ½ tablespoons Cajun seasoning 1 tablespoon olive oil
  • Pasta: 12 oz (340 g) fettuccine pasta
  • Sauce: 2 tablespoons unsalted butter 2 cloves garlic minced 1 cup (240 ml) heavy cream 8 oz (225 g) Velveeta cheese cubed ½ cup (50 g) grated Parmesan cheese ½ teaspoon black pepper ¼ teaspoon cayenne pepper (optional for extra heat) Salt to taste
  • Garnish: 2 tablespoons fresh parsley chopped Extra grated Parmesan cheese (optional)

Instructions

Step 1:
Bring a large pot of salted water to a boil. Cook the fettuccine according to package instructions until al dente. Drain and set aside reserving ½ cup pasta water.
Step 2:
While the pasta cooks pat chicken breasts dry. Rub both sides with Cajun seasoning.
Step 3:
In a large skillet heat olive oil over medium-high heat. Add chicken and cook 5–6 minutes per side or until golden and cooked through (internal temperature 165°F/74°C). Remove chicken let rest 5 minutes then slice thinly.
Step 4:
In the same skillet reduce heat to medium. Add butter and garlic sauté 1 minute until fragrant.
Step 5:
Stir in heavy cream and bring to a gentle simmer. Add Velveeta cubes stirring often until melted and smooth.
Step 6:
Add Parmesan cheese black pepper and cayenne pepper (if using). Stir until fully combined and creamy. If sauce is too thick add reserved pasta water a little at a time.
Step 7:
Toss cooked fettuccine in the sauce until well coated.
Step 8:
Divide pasta among plates. Top with sliced Cajun chicken. Garnish with parsley and extra Parmesan if desired.
This photo features a steaming bowl of Cajun Chicken Alfredo Fettuccine, perfectly garnished and ready to eat. Save
This photo features a steaming bowl of Cajun Chicken Alfredo Fettuccine, perfectly garnished and ready to eat. | hazeldish.com

This dish often sparks lively conversations at the dinner table and brings everyone together for seconds.

Required Tools

Large pot Large skillet Knife and cutting board Tongs or pasta fork Measuring cups and spoons

Allergen Information

Contains milk/dairy (Velveeta Parmesan cream butter) Contains wheat (fettuccine) Contains chicken Those with allergies should check ingredient labels for hidden allergens

Nutritional Information

Calories 670 Total Fat 32 g Carbohydrates 57 g Protein 41 g per serving

Golden chicken and the rich, cheesy sauce coat the Cajun Chicken Alfredo Fettuccine, a comforting meal. Save
Golden chicken and the rich, cheesy sauce coat the Cajun Chicken Alfredo Fettuccine, a comforting meal. | hazeldish.com

This creamy Cajun Chicken Alfredo brings warmth and comfort to any dinner occasion.

Recipe Help & Answers

How do I ensure the chicken stays juicy?

Pat the chicken dry before seasoning and avoid overcooking by cooking 5-6 minutes per side until just done. Let it rest before slicing.

Can I substitute Velveeta cheese with another type?

While Velveeta provides a smooth creaminess, you can use a blend of cheddar and cream cheese for a similar texture and flavor.

What’s the best way to keep the sauce creamy?

Simmer the cream gently and stir frequently as the cheese melts. Use reserved pasta water to loosen the sauce if needed.

How can I adjust the spice level in this dish?

Modify the amount of Cajun seasoning and cayenne pepper according to your heat preference or omit cayenne for mild flavor.

What sides pair well with this dish?

A crisp green salad and a chilled glass of Chardonnay complement the creamy and spicy flavors nicely.

Cajun Chicken Fettuccine Velveeta

Tender Cajun-spiced chicken and creamy Velveeta sauce coat al dente fettuccine for a comforting meal.

Prep Time
15 min
Time to Cook
25 min
Overall Time
40 min
Created by Isabel Grant


Skill Level Easy

Inspired By American (Cajun-inspired)

Makes 4 Number of servings

Dietary Details None specified

What You Need

Chicken

01 2 large boneless, skinless chicken breasts
02 1 ½ tablespoons Cajun seasoning
03 1 tablespoon olive oil

Pasta

01 12 oz fettuccine pasta

Sauce

01 2 tablespoons unsalted butter
02 2 cloves garlic, minced
03 1 cup heavy cream
04 8 oz Velveeta cheese, cubed
05 ½ cup grated Parmesan cheese
06 ½ teaspoon black pepper
07 ¼ teaspoon cayenne pepper (optional)
08 Salt, to taste

Garnish

01 2 tablespoons fresh parsley, chopped
02 Extra grated Parmesan cheese (optional)

How to Make It

Step 01

Cook the fettuccine: Bring a large pot of salted water to a boil. Cook fettuccine until al dente according to package directions. Drain, reserving ½ cup pasta water, and set aside.

Step 02

Prepare and season chicken: Pat chicken breasts dry and evenly coat both sides with Cajun seasoning.

Step 03

Cook chicken: Heat olive oil in a large skillet over medium-high heat. Sear chicken 5–6 minutes per side until golden and fully cooked (internal temperature 165°F). Remove and allow to rest for 5 minutes before slicing thinly.

Step 04

Sauté garlic in butter: Reduce skillet heat to medium. Add butter and minced garlic, sautéing for 1 minute until fragrant.

Step 05

Prepare cheese sauce: Stir in heavy cream, bring to a gentle simmer. Add Velveeta cubes, stirring frequently until fully melted and smooth.

Step 06

Incorporate seasonings and cheese: Blend in Parmesan cheese, black pepper, cayenne pepper if using, and salt. Stir until sauce is creamy. If sauce thickens too much, gradually add reserved pasta water to adjust consistency.

Step 07

Combine pasta and sauce: Toss cooked fettuccine in the sauce until evenly coated.

Step 08

Plate and garnish: Divide pasta onto serving plates, top with sliced Cajun chicken. Garnish with chopped parsley and additional Parmesan if desired.

Tools You’ll Need

  • Large pot
  • Large skillet
  • Knife and cutting board
  • Tongs or pasta fork
  • Measuring cups and spoons

Allergy Details

Review each ingredient for allergens. Always reach out to a healthcare professional for help if you’re unsure.
  • Contains milk/dairy products including Velveeta, Parmesan, cream, and butter
  • Contains wheat from fettuccine pasta
  • Contains poultry

Per-Serving Nutrition

Nutritional data is for general reference only. It shouldn't replace advice from your doctor.
  • Calorie Count: 670
  • Fats: 32 g
  • Carbohydrates: 57 g
  • Proteins: 41 g