Zesty Cajun Garlic Chicken

Featured in: Rustic Family Dinners

This vibrant dish combines tender chicken pieces with cheesy tortellini, all enveloped in a creamy Cajun garlic Parmesan sauce. Aromatic garlic, diced bell peppers, and a blend of Cajun seasoning bring a spicy depth, while the Parmesan cheese adds a rich, savory finish. Quick to prepare and perfect for weeknights, this fusion of American and Italian flavors satisfies cravings with a delightful kick and comforting creaminess.

Updated on Sat, 15 Nov 2025 13:32:00 GMT
Steaming hot Zesty Cajun Garlic Parmesan Chicken Tortellini, a creamy, cheesy pasta dish with chicken. Save
Steaming hot Zesty Cajun Garlic Parmesan Chicken Tortellini, a creamy, cheesy pasta dish with chicken. | hazeldish.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick.

I first made this for a busy Tuesday evening when my family was craving something comforting but exciting. The fusion of Cajun spice and creamy cheese became an instant favorite at our table.

Ingredients

  • Boneless skinless chicken breasts: 2 large, cut into bite-sized pieces
  • Refrigerated cheese tortellini: 500 g (18 oz)
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g), freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons, chopped (for garnish)
  • Optional: extra grated Parmesan for serving

Instructions

Cook tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Prepare chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 (to 7) minutes. Remove chicken from skillet and set aside.
Sauté vegetables:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3 (to 4) minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Add spices and cream:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add cheese and finish sauce:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Toss chicken and pasta:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Final heat through:
Cook for an additional 2 (to 3) minutes until heated through.
Serve:
Serve garnished with fresh parsley and extra Parmesan if desired.
Looking down at a bowl of Zesty Cajun Garlic Parmesan Chicken Tortellini, garnished with fresh parsley. Save
Looking down at a bowl of Zesty Cajun Garlic Parmesan Chicken Tortellini, garnished with fresh parsley. | hazeldish.com

One evening my kids surprised me by wanting seconds, and we ended up laughing around the dinner table while soaking up the sauce with slices of bread. It became one of our most requested meals for family nights.

Serving Suggestions

Pair this dish with crusty bread or garlic rolls to soak up every bit of the creamy Cajun sauce. A crisp white wine, like Sauvignon Blanc, complements the flavors perfectly.

Variations

Try substituting shrimp for chicken for a seafood twist, or add sautéed mushrooms for extra earthiness. If you prefer less heat, reduce the Cajun seasoning slightly, and skip the optional red pepper flakes.

Nutritional Information

Per serving: Calories: 620, Total Fat: 29 g, Carbohydrates: 53 g, Protein: 38 g. These values are approximate and may vary based on ingredient brands and substitutions.

Close-up of vibrant Zesty Cajun Garlic Parmesan Chicken Tortellini; chicken pieces nestled in a rich sauce. Save
Close-up of vibrant Zesty Cajun Garlic Parmesan Chicken Tortellini; chicken pieces nestled in a rich sauce. | hazeldish.com

Enjoy the bold flavors and creamy sauce, and let this vibrant Cajun garlic Parmesan chicken tortellini liven up your weeknight dinner rotation. This dish is sure to make even the busiest evenings special!

Recipe Help & Answers

Can I substitute shrimp for the chicken?

Yes, shrimp can be used instead of chicken for a seafood variation that pairs well with the creamy Cajun sauce.

What type of pasta works best for this dish?

Cheese tortellini is ideal for its tender, filled texture that complements the creamy sauce perfectly.

How can I increase the spice level?

Add a pinch of cayenne pepper or crushed red pepper flakes to the sauce for an extra spicy kick.

Is this dish suitable for a quick weeknight dinner?

Absolutely, it takes about 40 minutes total, making it a flavorful yet convenient choice for busy evenings.

What garnishes complement the flavors best?

Freshly chopped parsley and extra grated Parmesan provide a bright and savory finishing touch.

Can this dish be paired with any beverages?

A crisp white wine like Sauvignon Blanc pairs nicely, balancing the creamy and spicy elements.

Zesty Cajun Garlic Chicken

Tender chicken and cheesy tortellini simmered in a creamy Cajun garlic Parmesan sauce with a spicy kick.

Prep Time
15 min
Time to Cook
25 min
Overall Time
40 min
Created by Isabel Grant


Skill Level Easy

Inspired By American/Italian Fusion

Makes 4 Number of servings

Dietary Details None specified

What You Need

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 ounces refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 ½ cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 ½ teaspoon smoked paprika
03 ½ teaspoon black pepper
04 ½ teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley (for garnish)
03 Optional: extra grated Parmesan for serving

How to Make It

Step 01

Cook Tortellini: Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.

Step 02

Sauté Chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Season chicken pieces with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 to 7 minutes. Remove from skillet and set aside.

Step 03

Cook Vegetables: In the same skillet, add remaining olive oil and butter. Sauté diced onion and red bell pepper for 3 to 4 minutes until softened. Add minced garlic and cook for 30 seconds until fragrant.

Step 04

Create Sauce: Sprinkle remaining Cajun seasoning and smoked paprika over vegetables. Stir briefly, then pour in heavy cream. Bring to a gentle simmer, stirring frequently.

Step 05

Incorporate Cheese: Add grated Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning as needed.

Step 06

Combine Ingredients: Return cooked chicken and tortellini to the skillet. Toss gently to coat all components evenly in the sauce.

Step 07

Final Heating: Cook for an additional 2 to 3 minutes until everything is heated through.

Step 08

Serve: Plate the dish and garnish with fresh parsley and extra Parmesan cheese if desired.

Tools You’ll Need

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy Details

Review each ingredient for allergens. Always reach out to a healthcare professional for help if you’re unsure.
  • Contains wheat (tortellini), milk (cream, Parmesan, butter), and potentially eggs (tortellini). Verify packaging for allergens.

Per-Serving Nutrition

Nutritional data is for general reference only. It shouldn't replace advice from your doctor.
  • Calorie Count: 620
  • Fats: 29 g
  • Carbohydrates: 53 g
  • Proteins: 38 g